I have an interface that is not showing any activity. And I'm trying to determine what is causing the issue. I wanted to try and change the IP but I'm worried it will cause all the interfaces to restart.
Changing an IP will not affect other interfaces, best way to test it is to run a ping command from one of your hosts to the interface to see if it works. Typically it's VLAN tagging or MTU related, changing MTU will drop the interfaces associated with the subnet.